THIS PRODUCT IS INTENDED AS RESEARCH CHEMICAL ONLY

This designation allows the use of research chemical strictly for in vitro testing and laboratory experimentation only.

All product information available on this website is for educational purpose only.

Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only by handled by licensed, qualified professionals.

This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Ipamorelin 2mg

Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular formula: C38H49N9O5
Molar Mass: 711.85296
CAS number: 170851-70-4
PubChem: CID 20754357
Synonyms: Ipamorelin Acetate, IPAM, NNC-26-0161

Ipamorelin

BIOPEPTIDE IPAMORELIN

Peptides Global is using the most refined technology in order to obtain the highest quality and purity Ipamorelin Peptide.

PEPTIDE IPAMORELIN SPECIFICATION DETAILS

PEPTIDE IPAMORELIN POSOLOGY (NORMAL DOSAGE & CYCLE)

Composition : Box of 10 vials (1.8mg per vial)
Dilution : 2mL of sterile water
Frequency : 2 injections of 300mcg per day (before breakfast and before bed)
Dose per vial : 6 x 300mcg (1 vial for 3 days)
Dose per injection : 300mcg=0.33mL (33 units on the insulin syringe)
Therapy cycle : 3 months (1 box for 1 month)

The human body relies on very specific endocrine chemistry to change and grow throughout the years. From the time we are born the pituitary gland, located at the base of the skull releases potent hormones that direct the body to build bone, muscle, and tissue. As we age however, many chemical processes slow considerably, because they are no longer needed in quite the same way. Growth hormone, necessary to create lean muscle mass and strong bones decreases.

The Ipamorelin Advantage

Ipamorelin is a growth hormone releasing peptide (GHRP) that naturally stimulates the body’s own production of growth hormone. When taken properly, at the right intervals, Ipamorelin promotes strength, anti-aging, and healing. In individuals who want to build lean muscle mass and control body weight, Ipamorelin works by binding to specific receptors within cells. This process then stimulates particular responses.[3] Because it is classified as an “agonist”, Ipamorelin is able to effect cellular change by way of its five amino acids.

How it Works

Once Ipamorelin is injected subcutaneously, the pituitary gland is stimulated to release growth hormone within the body. Cells immediately begin to mobilize, moving toward the muscles to support growth and development. The effects of this Ipamorelin dose can last up to 3 hours without creating disfiguring bone and cartilage growth. The powerful pentapeptide works in conjunction with the body’s natural chemistry in a “pulsatile fashion” without depleting existing stores of growth hormone.[4] Because many of the side effects associated with direct Human Growth Hormone (HGH) use do not exist, including swelling of joints and Carpal Tunnel Syndrome, Ipamorelin can be used long-term.

Benefits of Ipamorelin

• Helps build lean muscle mass
• Helps regulate blood pressure
• Promotes anti-aging
• Regulates body temperature
• Improves sexual function
• Helps relieve pain
• Helps reduce body fat
• Helps build strength in muscles
• Helps promote muscle definition, density, hardness, and contours
• Helps promote greater testosterone production
• Helps create bone strength[5]
• Helps promote joint and ligament repair
• Helps promote healthy skin
• Helps smooth wrinkles
• Helps regenerate feelings of vitality and energy
• Improves sleep quality

Gentler GHRP with Fewer Side Effects

Many popular peptide releasers including, GHRP-6 and GHRP-2 work to stimulate the release of growth hormone secreted by the pituitary gland. Some of these also produce unwanted side effects when mimicking the hormone ghrelin, such as intense hunger.[1][2]

Ipamorelin is milder than most growth hormone releasing peptides (GHRP’s), but powerful enough to promote GH production. Some users do experience a headache or a “head rush” when first dosing, but most tolerate the synthetic peptide very well. When used properly as part of an overall diet and exercise regimen Ipamorelin is an excellent choice for individuals who want to supplement their workout.

Advantages include:

• No extreme spikes in cortisol or prolactin
• Increases Lean Body Mass
• Decreases body fat
• No major hunger spikes
• Improves mood and sleep
• Faster recovery from pain and soreness
• Efficient like GHRP-6
• Promotes gains
• Helps suppress somatostatin (growth hormone inhibitor)
• Ideal for dosing before bedtime
• Saturation does not desensitize the body to effects of Ipamorelin
• Long lasting effects

Many individuals are already doing the work with regular, intense physical training. Synthetic Ipamorelin merely maximizes the body’s full potential by working with its own natural chemistry. By stimulating the secretion of growth hormone, powerful GH pulses are released that promote energy, vitality, strength, and growth that lasts for hours. There’s nothing better than utilizing the body’s own physical processes to create a better body.

References

1Klok, M., Jakobsdottir, S. and Drent, M. (2007) ‘The role of leptin and ghrelin in the regulation of food intake and body weight in humans: A review’, Obesity reviews : an official journal of the International Association for the Study of Obesity., 8(1), pp. 21–34.

2Laferrère, B., Abraham, C., Russell, C.D. and Bowers, C.Y. (no date) ‘Growth hormone releasing peptide -2 (GHRP-2), like ghrelin, increases food intake in healthy men’, 90(2).

3NCI drug dictionary (2011) Available at: https://www.cancer.gov/publications/dictionaries/cancer-drug?cdrid=719246 (Accessed: 9 December 2016).

4Raun, K., Hansen, B., Johansen, N., Thøgersen, H., Madsen, K., Ankersen, M. and Andersen, P. (1998) ‘Ipamorelin, the first selective growth hormone secretagogue’, European journal of endocrinology., 139(5), pp. 552–61.
Vriese, D. and Delporte, C. (2007) ‘Influence of ghrelin on food intake and energy homeostasis’, Current opinion in clinical nutrition and metabolic care., 10(5), pp. 615–9.

5(No Date) Available at: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.528.9286&rep=rep1&type=pdf(Accessed: 9 December 2016).

THIS PRODUCT IS INTENDED AS RESEARCH CHEMICAL ONLY

This designation allows the use of research chemical strictly for in vitro testing and laboratory experimentation only.

All product information available on this website is for educational purpose only.

Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only by handled by licensed, qualified professionals.

This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Hgh Fragment (176-191)

Growth Hormone peptide fragment 176-191, also known as HGH Frag 176-191, is a modified form of amino acids 176-191 of the GH polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the Growth Hormone molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance. It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone. Like Growth Hormone, the hgH fragment 176-191 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.

Laboratory Tests and Fat Loss

In laboratory tests on fat cells from rodents, pigs, dogs, and humans, the hgH fragment released fat specifically from obese fat cells but not from lean ones, reduced new fat accumulation in all fat cells, enhanced the burning of fat. In rodents (rats and mice), hgH fragment reduced body fat in obese animals but, enhanced fat burning without changing food consumption or inducing growth (as it does not increase IGF levels) or any other unwanted Growth Hormone effect. Research dosages of 500mcg of the hgH fragment 176-191 daily for 30 days did show a reduction of body fat in the mid abdominal area in both obese, over-weight, and average built people.

Fragment 176-191 as an Active HGH Truncated Peptide

hgH fragment 176-191 is an analog of the growth hormone-releasing factor (GRF) which signals the effects of growth hormone. It is a 15-mer peptide residue of the C-terminus of HGH to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits. Studies claimed that it actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.

These segments of the synthetic peptide hgH 176-191 have been investigated for their in vivo effects in laboratory mice musculus. Research results have shown that hgH 176-191 have resulted to a short-period increase in blood glucose and a more sustained increase in plasma insulin, together with other fragments such as 172-191, 177-191 and 178-191. In addition, the researchers have suggested that functionality of the peptide depends not only in the informational sequence but should also have the correct physical configuration (Ng and Borstein 1978). Also, this fragment, being a region of high accessibility to proteases and also rich in proline, have been demonstrated to affect the conformational change in the cytoplasmic domain of the band 3 of erythrocyte membrane protein by serving as the hinge for the pivoting of the two subdomains. This then suggest that such residue is significant in conformational changes be serving as sites for peripheral protein binding in some body cells (Low et al. 1984).

In another study of Ng et al. (2000) on animal subjects, they found out that a 500mcg dosage of the said hormone increased the lipolytic activity in adipose tissues without having negative influence in the blood glucose level. Furthermore, though it behaves like a human growth hormone (hgH), it does not causes hyperglycemia because it does not compete with hgH receptors (Wu et al. 1993). Because of such effects, researchers have suggested that it might be used for the elimination of excess abdominal fat which is a significant aspect of HIV-associated lipodystrophy.

The (hgH fragment 176-191) exhibits the ability to burn through stubborn adipose tissue, while increasing energy expenditure, muscle mass, and fat oxidation. All studies have pointed to the fact that the fragment is an effective treatment for obesity and fat loss, and much safer than its Human Growth Hormone counterpart.

THIS PRODUCT IS INTENDED AS RESEARCH CHEMICAL ONLY

This designation allows the use of research chemical strictly for in vitro testing and laboratory experimentation only.

All product information available on this website is for educational purpose only.

Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only by handled by licensed, qualified professionals.

This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

THE MELANOTAN PEPTIDE : HOW TO TAN LIKE A STAR

If you’ve never heard of Melanotan 2, don’t be surprised. tanning peptide is a type of peptide that stimulates the production of melanin in the body to provide a deep, natural tan. Melanin is actually your body’s natural response to UV damage, darkening the skin slightly to protect it from further damage.

Of course, the problem with exposure to the sun is that getting a full body tan requires plenty of exposure to potentially dangerous amounts of UV radiation which can lead to skin cancer and other dangerous health problems.

How it works?

This peptide is a designed to stimulate the body’s tanning response with minimal exposure to sunlight. This can be a wonderful way for those with fair to very fair skin to get tanned without having to spend weeks in the sun and going through the burn and heal process.

By using MT2, users experience quicker tanning and and faster healing to damaged skin cells than would otherwise be possible. Because of this, it is especially suited to those who’s skin is pale; those who are at greatest risk of developing skin cancer.

How is MT2 Used?

This peptide is shipped by vial in a powder dried form that is reconstituted using sterile water and then injected under the skin where is absorbed into the skin itself and spread throughout.

Benefits

Minimal UV Exposure: MT2 still requires exposure to sunlight to be effective, however it requires significantly less time to develop a tan than without the peptide.

Flexibility: Users can take a small loading dose and continue dosing until they reach their desired pigmentation, after which time they only need to dose once every couple of weeks to keep the same pigment.

Lasting Tan: Even if dosage is stopped entirely, a warm tan can last for months on end without exposure to the sun. By contrast, tans developed naturally fade very quickly in a matter of days or weeks depending person skin type.

Notes and Considerations

Research: It can be hard to imagine that seemingly reputable websites would sell an ineffective product, however research should be done before making a purchase as many vendors will offer products that are inferior or outright falsely labeled as MT II peptide.

Products: There are many products on the online market being sold as tanning peptides; everything from nasal spray to pills to sprinkle on flakes. Despite their claims of being easier to use, safer and more effective. These products are fake. The peptide is too large to pass through the sinus membrane, making it ineffective as a spray and the enzymes in your stomach would dissolve any orally taken peptides. Truly, the only real way to get the full effect from your regimen is to use injections. People around the world and especially in UK, USA, Australia buy melanotan to get deep, long lasting tan with as little uv ray exposure as possible.

MT 1 and MT 2 are synthetic analogues of the alpha-melanocyte stimulating peptide hormone Alpha-MSH. This hormone aids skin cells to produce greater quantities of Melanin. Therefore MT-1 and MT-2 mimic this hormone and encourage the production of more Melanin. Melanin is a dark pigment in the skin that can provide some protection from the UV rays of the sun.

Alpha-MSH produces Melanin, along with other melanocortins, affects the following functions: skin pigmentation, general libido, appetite, physical arousal. MT II exclusively has been noted to have a positive effect on libido and physical arousal in both sexes.

Exposure to ultraviolet (UV) light prompts an increased release of Alpha-MSH, which in turn stimulates the production of Melanin in the skin. The more Melanin produced the greater pigmentation level becomes, making the skin progressively darker and tan lasts significantly longer. This makes Melanotan peptide unique, people do not require as much exposure to UV light to produce more Melanin, very attractive for people wishing to develop greater tanning of the skin in fastest way possible.

How does MT-1 compare to MT-2? In terms of darkening the pigmentation of skin to enhance and individuals tan, both types have been proven to work in a number of clinical trials. However, the side effects using MT-2 are more common, but offsetting this is the fact that the darkening effect using MT-2 can be seen faster. It’s important to note that the dosages for Melanotan and Melanotan 2 are different. For example, a sometimes recommended beginning dose of MT1 is 1mg, while a beginning dose of MT2 is often only 0.25mg.
Side effects: Nausea, fatigue, facial flushing, reaction at injection site, appetite suppresion. The potential for side effects to occur increases with an increased dose of Melonotan, and decreases both with a lesser dose and with regular administration. The exception to this is physical signs of sexual arousal, namely male erection when using MT2. So it is important that users of MT II are aware of this before administering.

Conclusion

It bears understanding that this type of peptide is not a treatment or cure for anything, nor should it be considered a preventative measure to skin cancer. While this tanning peptide is known to protect the skin through the natural tanning process, it is not in and of itself a foolproof UV shield, however it is an excellent way for those who don’t tan otherwise to get rich golden tans without as much exposure to the sun. People around the world buy melanotan in  This is short insight of MT II peptide.

THIS PRODUCT IS INTENDED AS RESEARCH CHEMICAL ONLY

This designation allows the use of research chemical strictly for in vitro testing and laboratory experimentation only.

All product information available on this website is for educational purpose only.

Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only by handled by licensed, qualified professionals.

This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Description

AOD 9604

AOD 9604 is a modified form of amino acids 176-191 of the GH polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the GH molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance.

It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone. Like Growth Hormone, AOD 9604 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.

Recent findings have shown, in addition to its fat loss properties, AOD 9604 possesses many other regenerative properties associated with growth hormone. Currently trials are underway to show the application of AOD 9604 in osteoarthritis, hypercholesterolemia, bone and cartilage repair. AOD 9604 has an excellent safety profile, recently obtaining Human GRAS status in the USA.

Research

Safety and Tolerability of the Hexadecapeptide AOD 9604 in Humans

Heike Stier, Evert Vos, David Kenley

Background: The human growth hormone (hGH) has properties making it a potential candidate to treat obesity. AOD 9604 is a peptide fragment of the C-terminus of hGH (Tyr-hGH177-191), which harbors the fat reducing activity of hGH, without its negative effects. In this paper the safety data of AOD 9604 obtained in clinical trials are summarized.

Methods: Six randomized, double-blind, placebo-controlled trials were performed with AOD 9604. Special
focus was given to undesired effects associated with hGH treatment: increases in IGF-1 levels, insulin resistance, and impaired glucose tolerance. Blood samples were analyzed for presence of anti-AOD 9604 antibodies to exclude immunogenicity.

Results: AOD 9604 had no effect on serum IGF-1 levels, which confirms the hypothesis that AOD 9604 does not act via IGF-1. Results of oral glucose tolerance test demonstrated that, in contrast with hGH, AOD 9604 has no negative effect on carbohydrate metabolism. There were no anti-AOD 9604 antibodies detected in any of the patients selected for antibody assay. In none of the studies did a withdrawal or serious adverse event occur related to intake of AOD 9604.

Conclusion: AOD 9604 displayed a very good safety and tolerability profile indistinguishable from placebo.

AOD 9604 did not result in any of the adverse effects associated with full-length hGH treatment.

Protocol

Content and Potency: 2 x 5ml at 1200mcg/ml ready-to-inject SUBCUTANEOUS.
Suggested dosage: 0.25ml daily for 40 days.
Transdermal Option: 300mcg/mL x 40mL – Apply 1mL daily for 40 days.